What has happened to gene therapy?

Trials have demonstrated the feasibility of gene therapy in correcting the gene defect in monogenic disorders such as severe combined immune deficienc y and cystic fibrosis, but there are still obstacles and ethical issues to overcome. Conclusion With appropriate research, better delivery strategies and adhere nce to good standard clinical research and practice, gene therapy research will lead to clinical implementation in monogenic and multifactorial disord ers including cancer, neurodegenerative disorders and vascular disease.