Effect of immunomodulator from Lactobacillus delbrueckii on therapeutic efficacy of cyclophosphamide in mice with Lewis carcinoma

Authors
Meniok, TA Voyejkova, IM Yudina, OY Mosienko, VS Shynkarenko, LN Savtsova, ZD
Citation
Ta. Meniok et al., Effect of immunomodulator from Lactobacillus delbrueckii on therapeutic efficacy of cyclophosphamide in mice with Lewis carcinoma, EXP ONCOL, 22(4), 2000, pp. 211-214
Citations number
20
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
EXPERIMENTAL ONCOLOGY
ISSN journal
02043564 → ACNP
Volume
22
Issue
4
Year of publication
2000
Pages
211 - 214
Database
ISI
SICI code
0204-3564(200012)22:4<211:EOIFLD>2.0.ZU;2-Y
Abstract
Results of investigation of peripheral blood, lymphoid organs, and intestin al epithelium showed that blasten (immunomodulator from Lactobacillus Delbr ueckii) was cap able of preventing cyclophosphamide-induced cytosuppression . Moreover, blasten augmented the therapeutic efficacy of cyclophosphamide in mice with Lewis carcinoma. This augmentation manifested itself both in a n enhanced tumor growth inhibition and in a lower metastasizing.