Analysis of the polar fraction of Haitian vetiver oil

The polar part of commercial Haitian vetiver oil was converted to the methy l ethers, and this product separated by distillation and repeated flash chr omatography (FC). The following new (nor-) sesquiterpene alcohols were isol ated as their methyl ethers and identified by their H-1- and C-13-NMR spect ra: 12-nor-ziza-6(13)-en-2 beta- (2) and -2 alpha -ol (3), eudesma-4(15),7- dien-3 beta- (7) and -2 beta -ol (18), eudesma-3,5-dien-1 alpha -ol (26), e remophila-1(10),4(15)-dien-2 alpha -ol (31), eremophila-1(10),11-dien-2 alp ha -ol (nootkatol, 38), guaia-1(5),11-dien-3-ol(11), spirovetiva-3,7(11)-di en-12-ol (42), preziza-7(15)-en-3 alpha -ol (14) and helifol-1-en-14-ol (sy n. khusien-14-ol, 12). Furthermore, the hemi-acetal 7,10-epoxy-salvialan-10 -ol (8) was identified. The structure of some artefacts formed by alkylatio n of beta -vetivone 52 (-->M 39, M 43) and of 11,12,13-tri-nor-eudesmenone (-->16, 17) was also elucidated. Copyright (C) 2000 John Wiley & Sons, Ltd.