EXPRESSION OF DOPAMINE D2 RECEPTOR MESSENGER-RNA ISOFORMS IN THE CAROTID-BODY OF RAT, CAT AND RABBIT

Authors
BAIRAM A KHANDJIAN EW
Citation
A. Bairam et Ew. Khandjian, EXPRESSION OF DOPAMINE D2 RECEPTOR MESSENGER-RNA ISOFORMS IN THE CAROTID-BODY OF RAT, CAT AND RABBIT, Brain research, 760(1-2), 1997, pp. 287-289
Citations number
16
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
760
Issue
1-2
Year of publication
1997
Pages
287 - 289
Database
ISI
SICI code
0006-8993(1997)760:1-2<287:EODDRM>2.0.ZU;2-6
Abstract
Using the Reverse transcription-Polymerase chain reaction, we detected dopamine D2 receptor mRNA short and long isoforms in the adult caroti d body of rats, cats, and rabbits. For these animals, the relative sho rt/long ratios were 0.60, 0.65 and 0.57, respectively. Our results sug gest that the variety of dopamine effects on carotid chemoreceptor act ivity, that has been related to species differences, may not be depend ent on the expression levels of the dopamine D2 receptor mRNA isoforms in the studied species. (C) 1997 Elsevier Science B.V.