Can cerebral blood volume be measured reproducibly with an improved near infrared spectroscopy system?

Citation
Mjt. Van De Ven et al., Can cerebral blood volume be measured reproducibly with an improved near infrared spectroscopy system?, J CEREBR B, 21(2), 2001, pp. 110-113
Citations number
19
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
ISSN journal
0271678X → ACNP
Volume
21
Issue
2
Year of publication
2001
Pages
110 - 113
Database
ISI
SICI code
0271-678X(200102)21:2<110:CCBVBM>2.0.ZU;2-A
Abstract
In some circumstances, cerebral blood volume (CBV) can be used as a measure for cerebral blood flow. A new near infrared spectroscope was used for det ermining the reproducibility of CBV measurements assessed by the O-2-method . Twenty-seven healthy subjects were investigated. An intrasubject coeffici ent of variation (CV) was calculated. based on four identical episodes of d esaturation-resaturation (O-2- method) procedures for CBV measurements. Two trials were performed, with (trial 1) and without (trial 2) disconnecting the equipment. A mean CV of 12.6% and 10.0% was found in trial I and 2. res pectively. Cerebral blood volume values yield 3.60 +/- 0.82 mL 100 g(-1). C erebral blood volume could be measured reproducible in adults using near in frared spectroscopy, if the arterial desaturation is limited to approximate ly 5% from baseline level.