Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera

Authors
Watarai, S Yokota, K",Tana,"Kishimoto, T Kanadani, T Taketa, K Oguma, K
Citation
S. Watarai et al., Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera, J CLIN MICR, 39(2), 2001, pp. 798-800
Citations number
14
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
2
Year of publication
2001
Pages
798 - 800
Database
ISI
SICI code
0095-1137(200102)39:2<798:RBSTHS>2.0.ZU;2-5
Abstract
The relationship between differential susceptibility to hemolytic-uremic sy ndrome (HUS) and levels of globotriaosylceramide (Gb3) in serum was studied in patients infected with verotoxin-producing Escherichia coli (VTEC). The serum Gb3 levels in patients with HUS were lower than these in diarrheal p atients without subsequent HUS or in patients without clinical symptoms, in dicating that individuals with a lower content of serum Gb3 show a higher i ncidence of HUS following VTEC infection.