Jg. Xu et al., High-pathogenicity island of Yersinia spp. in Escherichia coli strains isolated from diarrhea patients in China, J CLIN MICR, 38(12), 2000, pp. 4672-4675
The high-pathogenicity island (HPI) of Yersinia has been observed in 93% of
60 enteroadhesive Escherichia coli strains and 80% of E. coli strains isol
ated from blood samples. In the present study we investigated 671 fecal sam
ples from patients with diarrhea in Shandong Province, China, and isolated
HPI-harboring E. coli from 6.26% of the samples. The isolation rates for pa
tients with diarrhea in three age groups, 10 to 20, 30 to 40, and 50 to 60
years, were 6.70, 12.35, and 10.81%, respectively. Therefore, HPI-harboring
E. coli is the third most frequently isolated enteric pathogen from patien
ts with diarrhea. Vomiting and abdominal pain were recorded for 33,33 and 6
6.67% of the patients, respectively. Stools with blood were observed for 9.
52% of the patients. Twenty-four of 42 (57%) patients experienced a tempera
ture over 37.4 degreesC. These observations indicate that HPI-harboring E.
call is one of the major causes of diarrheal disease in China and that the
clinical symptoms caused by HPI-harboring E. coil differ from those caused
by enteroadhesive E. coli.