Can pooling be used for seroprevalence studies of hepatitis C?

Authors
Stephens, GM Raboud, JM Karakas, L Sherlock, CH
Citation
Gm. Stephens et al., Can pooling be used for seroprevalence studies of hepatitis C?, J CLIN MICR, 38(11), 2000, pp. 4264-4265
Citations number
7
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
38
Issue
11
Year of publication
2000
Pages
4264 - 4265
Database
ISI
SICI code
0095-1137(200011)38:11<4264:CPBUFS>2.0.ZU;2-2
Abstract
Two hepatitis C antibody assays were used to test diluted positive sera. Di lutions of 1 in 5, 1 in 10, and 1 in 20 all resulted in loss of reactivity, with the greatest losses occurring in samples with low and moderate reacti vities. These results disqualify pooling as a strategy for seroprevalence s tudies and screening programs.