Hydrophobic volume effects in albumin solutions

Authors
Schrade, P Klein, H Egry, I Ademovic, Z Klee, D
Citation
P. Schrade et al., Hydrophobic volume effects in albumin solutions, J COLL I SC, 234(2), 2001, pp. 445-447
Citations number
12
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF COLLOID AND INTERFACE SCIENCE
ISSN journal
00219797 → ACNP
Volume
234
Issue
2
Year of publication
2001
Pages
445 - 447
Database
ISI
SICI code
0021-9797(20010215)234:2<445:HVEIAS>2.0.ZU;2-6
Abstract
Density measurements of aqueous albumin solutions as a function of concentr ation and temperature are reported. The solvents were H2O, D2O, and a physi ological H2O-based buffer, An anomaly of the density at very small concentr ations of albumin in D2O was found. Furthermore, the partial specific volum e of albumin is remarkably different in D2O and H2O, We attribute both effe cts to structural differences of the solvents. (C) 2001 Academic Press.