Recent progress in asymmetric intermolecular C-H activation by rhodium carbenoid intermediates

Authors
Davies, HML Antoulinakis, EG
Citation
Hml. Davies et Eg. Antoulinakis, Recent progress in asymmetric intermolecular C-H activation by rhodium carbenoid intermediates, J ORGMET CH, 617(1), 2001, pp. 47-55
Citations number
59
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
617
Issue
1
Year of publication
2001
Pages
47 - 55
Database
ISI
SICI code
0022-328X(20010115)617:1<47:RPIAIC>2.0.ZU;2-S
Abstract
Intermolecular C-H insertion with rhodium carbenoid intermediates is a very promising method for C-H activation. By using carbenoids derived from viny l and phenyl diazoacetates, highly selective C-H insertions can be achieved . High asymmetric induction is obtained when dirhodium tetraprolinates (24- 27) are used as catalysts. Remarkably, with certain substrates, excellent d iastereocontrol is also possible. (C) 2001 Elsevier Science B.V. All rights reserved.