We describe a patient with multicentric reticulohistiocytosis (MR), who pre
sented with 2 different clinical types of lesions. Some were characteristic
for MR in that they were deeply set, small, firm papules. Many others were
larger, soft, and even sessile, like neurofibromas. Histopathologic featur
es of both types of lesions revealed MR. To our knowledge, this is the firs
t report of lesions of MR mimicking neurofibromas.