Malignant spiradenoma: Report of two cases and literature review

Spiradenoma is a benign skin adnexal neoplasm that usually appears as a sol itary nodule in any area of the body. There have been only 33 reports on ma lignant transformation of a benign eccrine spiradenoma since the first desc ription by Dabska in 1972. Most cases have originated on a long-standing cu taneous lesion. These tumors can behave in an aggressive fashion, and some have led to the patient's death. We report 2 new cases of this rare neoplas m affecting 2 men, 92 and 72 years of age, comment on the clinical and path ologic features of our cases, and review the literature concerning this les ion.