B. Dousset et al., PROTEIN-LOSING ENTEROPATHY SECONDARY TO HEPATIC VENOUS OUTFLOW OBSTRUCTION AFTER LIVER-TRANSPLANTATION, Journal of hepatology, 27(1), 1997, pp. 206-210
A 42-year-old man with a history of repeated abdominal surgery and 12
mph node tuberculosis underwent orthotopic Liver transplantation for p
rimary sclerosing cholangitis, Two years after transplantation, this p
atient developed a severe protein-losing enteropathy with no evidence
of cardiac disease or lymphoproliferative disorder, Imaging work-up re
vealed hemodynamically significant stenosis of the supra-hepatic caval
anastomosis, which was treated by percutaneous balloon angioplasty, A
ll clinical and biochemical disorders resolved within 1 month after pe
rcutaneous dilatation, but relapsed simultaneously with recurrent anas
tomotic stenosis 15 months Inter, Repeat caval angioplasty resulted in
rapid recovery, which strongly suggests that hepatic venous outflow o
bstruction was responsible for the protein-losing enteropathy in this
patient.