Esophageal carcinoma was observed in an eight-year-old, castrated male, Jap
anese domestic cat. Histologically, this neoplasm consisted of two differen
t growth patterns, squamous cell carcinoma and adenocarcinoma. The results
of immunohistochemical examination supported the fact that the two kinds of
neoplastic cells have different characteristics. The tumor was, therefore,
diagnosed as adenosquamous carcinoma. Esophageal tumors in the cat are ver
y rare and, if any, neither adenocarcinoma nor adenosquamous carcinoma has
been reported up to the present.