Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth

Authors
Hoiby, N Johansen, HK Moser, C Song, ZJ Ciofu, O Kharazmi, A
Citation
N. Hoiby et al., Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth, MICROBES IN, 3(1), 2001, pp. 23-35
Citations number
137
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
3
Issue
1
Year of publication
2001
Pages
23 - 35
Database
ISI
SICI code
1286-4579(200101)3:1<23:PAATIV>2.0.ZU;2-M
Abstract
The biofilm mode of growth is the survival strategy of enviromental bacteri a like Pseudomonas aeruginosa. Such P. aeruginosa biofilms also occur in th e lungs of chronically infected cystic fibrosis patients, where they protec t the bacteria against antibiotics and the immune response. The lung tissue damage is due to immune complex mediated chronic inflammation dominated by polymorphonuclear leukocytes releasing proteases and oxygen radicals. (C) 2001 Editions scientifiques et medicales Elsevier SAS.