Improvement of a critical intermediate step in the synthesis of a nitroxide-based spin-labeled deoxythymidine analog

Authors
Powell, JH Johnson, EM Gannett, PM
Citation
Jh. Powell et al., Improvement of a critical intermediate step in the synthesis of a nitroxide-based spin-labeled deoxythymidine analog, MOLECULES, 5(12), 2000, pp. 1244-1250
Citations number
9
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
MOLECULES
ISSN journal
14203049 → ACNP
Volume
5
Issue
12
Year of publication
2000
Pages
1244 - 1250
Database
ISI
SICI code
1420-3049(200012)5:12<1244:IOACIS>2.0.ZU;2-W
Abstract
Methods to reduce the carboxylic acid moiety in 3-carboxy-2,2,5,5-tetrameth yl-pyrrolin-1-oxyl to an alcohol as an intermediate toward the correspondin g aldehyde have been explored and an improved method has been developed.