The completion of the human genome will greatly accelerate the development
of a new branch of science - evolutionary genomics. We can now directly add
ress important questions about the evolutionary history of human genes and
their regulatory sequences. Computational analyses of the human genome will
reveal the number of genes and repetitive elements, the extent of gene dup
lication and compositional heterogeneity in the human genome, and the exten
t of domain shuffling and domain sharing among proteins. Here we present so
me first glimpses of these features.