Evolutionary analyses of the human genome

Citation
Wh. Li et al., Evolutionary analyses of the human genome, NATURE, 409(6822), 2001, pp. 847-849
Citations number
5
Categorie Soggetti
Multidisciplinary,Multidisciplinary,Multidisciplinary
Journal title
NATURE
ISSN journal
00280836 → ACNP
Volume
409
Issue
6822
Year of publication
2001
Pages
847 - 849
Database
ISI
SICI code
0028-0836(20010215)409:6822<847:EAOTHG>2.0.ZU;2-0
Abstract
The completion of the human genome will greatly accelerate the development of a new branch of science - evolutionary genomics. We can now directly add ress important questions about the evolutionary history of human genes and their regulatory sequences. Computational analyses of the human genome will reveal the number of genes and repetitive elements, the extent of gene dup lication and compositional heterogeneity in the human genome, and the exten t of domain shuffling and domain sharing among proteins. Here we present so me first glimpses of these features.