Bogorol A produced in culture by a marine Bacillus sp reveals a novel template for cationic peptide antibiotics

Authors
Barsby, T Kelly, MT Gagne, SM Andersen, RJ
Citation
T. Barsby et al., Bogorol A produced in culture by a marine Bacillus sp reveals a novel template for cationic peptide antibiotics, ORG LETT, 3(3), 2001, pp. 437-440
Citations number
25
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
3
Year of publication
2001
Pages
437 - 440
Database
ISI
SICI code
1523-7060(20010208)3:3<437:BAPICB>2.0.ZU;2-E
Abstract
[GRAPHICS] Bogorol A (1), a novel peptide antibiotic active against MRSA and VRE, has been isolated from cultures of a marine Bacillus sp, collected in Papua New Guinea, The structure of bogorol A was elucidated by a combination of spec troscopic analyses and chemical degradation. Bogorol A illustrates a new st ructural template for "cationic peptide antibiotics".