Because the outcome of a large clinical series of patients with juxtapositi
on of the atrial appendages (JAA) has not previously been reported, a retro
spective study was performed on patients diagnosed with JAA at a tertiary m
edical center. Patients with JAA were identified through a computerized dat
abase search, and echocardiograms and medical records of patients with JAA
were reviewed. Twenty-two patients with JAA were identified, with an overal
l incidence of 0.28%. All but 2 patients were diagnosed prospectively with
JAA by echocardiography. The lesion-specific incidences and associated lesi
ons were similar to those of large autopsy and surgical series. Abnormal co
notruncal anatomy was more frequently seen with juxtaposition of the right
atrial appendage (JRAA) vs juxtaposition of the left atrial appendage (JLAA
) (14/15 vs 4/7), as was atrial outlet obstruction (6/15 vs 2/7). JLAA was
more frequently associated with complex atrioventricular anatomy (3/7 vs 1/
15). Patients with JAA underwent single ventricle palliation in 11/22 cases
with 6 deaths; biventricular repair was performed in 8/22 cases with no de
aths. Surgical outcomes for patients with JRAA and JLAA were similar, and s
urvival was predominantly influenced by suitability for biventricular repai
r.