Purpose: An evaluation was made of sexual and bladder dysfunction combined
with quality of life (QoL) score after a proctocolectomy with total mesorec
tal excision (TME) for benign diseases. Methods: An in-depth questionnaire
was mailed to all patients (n = 94) who had undergone a proctocolectomy wit
h TME followed by an ileal pouch-anal anastomosis (IPAA) in the period from
1989 through 1994. Seventy-six patients responded (81%) with a mean age of
34 +/- 10.6 years and a mean follow-up of 33 +/- 18.3 months. Results: Sex
ual activity, satisfaction and libido were preserved better in males than i
n females. Severe sexual dysfunction was found in two males (permanent retr
ograde ejaculation) and in one female (complete vaginal dryness). No severe
bladder dysfunction was found, although minor dysfunction, such as stress
and urge incontinence, occurred frequently. QoL was significantly increased
postsurgery. Moreover, no evident correlation was demonstrated between QoL
and sexual and bladder dysfunction. Conclusion: A relatively low incidence
of severe sexual and bladder disorders was found following proctocolectomy
with TME and IPAA, whereas minor dysfunction was a relatively common findi
ng. Nevertheless. a significant increase was found in postoperative QoL com
pared to preoperative QoL.