ER calcium and the functions of intracellular organelles

Authors
Ashby, MC Tepikin, AV
Citation
Mc. Ashby et Av. Tepikin, ER calcium and the functions of intracellular organelles, SEM CELL D, 12(1), 2001, pp. 11-17
Citations number
86
Categorie Soggetti
Cell & Developmental Biology
Journal title
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
ISSN journal
10849521 → ACNP
Volume
12
Issue
1
Year of publication
2001
Pages
11 - 17
Database
ISI
SICI code
1084-9521(200102)12:1<11:ECATFO>2.0.ZU;2-5
Abstract
Cytosolic calcium has long been known as a second messenger of major signif icance. Recently it has become apparent that calcium stored in cellular org anelles can also be an important regulator of cellular functions. The endop lastic reticulum (ER) is usually the largest store of releasable calcium in the cell. The diverse signalling functions of calcium populating the endop lasmic reticulum and its interactions with other organelles are illustrated in Figure 1 and described in this paper.