This review critically analyses the role of urgent biliary decompression in
the management of acute gallstone pancreatitis with the emphasis on endosc
opic retrograde cholangiopancreatography (ERCP) and endoscopic sphincteroto
my (ES). In an analysis of currently available prospective randomised trial
s the role of routine urgent ERCP with or without ES in patients with predi
cted severe pancreatitis is challenged. Patients with persistent biliary ob
struction and associated cholangitis appear to be the only subgroup who may
benefit from urgent biliary intervention.