Absolute configuration of N-[(-)-2-(7-methoxy-1,2,3,4-tetra- hydro-1-naphthyl)ethyl]cyclopropyl-carboxamide, a highly potent and selective melatonin analogue

Authors
Guelzim, A Belloli, E Yous, S Vaccher, C
Citation
A. Guelzim et al., Absolute configuration of N-[(-)-2-(7-methoxy-1,2,3,4-tetra- hydro-1-naphthyl)ethyl]cyclopropyl-carboxamide, a highly potent and selective melatonin analogue, ACT CRYST C, 57, 2001, pp. 100-101
Citations number
16
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
57
Year of publication
2001
Part
1
Pages
100 - 101
Database
ISI
SICI code
0108-2701(200101)57:<100:ACONH>2.0.ZU;2-L
Abstract
The title compound, C17H23NO2, a tetrahydronaphthalenic analogue of melaton in, crystallizes in the monoclinic space group P2(1) with one molecule in t he asymmetric unit. The crystal structure has been determined by X-ray anal ysis at room temperature. The absolute configuration of this compound was d etermined unambiguously as R at the chiral naphthalene C-1 position.