Neurological disease among women with silicone breast implants in Denmark

Objectives - To investigate the risk of neurological disease among women wi th cosmetic breast implants. Material and methods - We identified 1653 wome n who had undergone breast implant surgery at private clinics in Denmark an d a comparison cohort of 1736 women who underwent other types of cosmetic s urgery at the same clinics. Ratios of observed-to-expected numbers of hospi talizations for neurological disease in the private implant and comparison cohorts were calculated, separately and combined with data from updated pub lic hospital cohorts. Results - The occurrence of neurological disease in t he private clinic implant cohort was comparable to that in the general popu lation. A similar risk pattern was observed in the private clinic compariso n cohort. When data for these private clinic cohorts were combined with upd ated data for public hospital cohorts, excess risks for neurological disord ers were seen in both implant and comparison cohorts, reaching statistical significance only in the comparison cohort. Conclusion - Our findings indic ate no causal association between silicone breast implants and neurological disease.