Citation
Wj. Cantor et al., Effectiveness and safety of Abciximab after failed thrombolytic therapy, AM J CARD, 87(4), 2001, pp. 439
Citations number
18
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149
→ ACNP
Volume
87
Issue
4
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010215)87:4<439:EASOAA>2.0.ZU;2-1
Abstract
Among 214 patients treated with abciximab within 24 hours of full-dose thro
mbolytic therapy, major bleeding occurred in 50 patients (23%; 95% confiden
ce interval [Cl] 18% to 30%) and intracranial hemorrhage occurred in 3 pati
ents (1.4%; 95% Cl 0.3% to 4%). The independent multivariate predictors of
major bleeding were age (odds ratio [OR] 1.53/10 years, 95% Cl 1.05 to 2.21
, p = 0.03), time from thrombolytic to abciximab (OR 0.91/hour, 95% Cl 0.83
to 0.99, p = 0.03), and intra-aortic balloon pump insertion (OR 4.42, 95%
Cl 2.00 to 9.72, p = 0.0002).