Fourteen patients with suspected leiomyoma of the esophagus were studi
ed by endoscopic ultrasonography, computed tomography, endoscopy and b
arium swallow. The results were correlated with the histology of the r
esected specimens: in 2 patients with a peduncolated leiomyoma origina
ting from the second echographic layer, endoscopic resection was perfo
rmed. Endoscopic ultrasonography was superior to other imaging techniq
ues in detection and staging of leiomyoma because it can determine the
layer of origin, the direction of the growth and the consistency of t
he tumor.