RESECTION OF HEPATIC METASTASES FROM COLORECTAL-CANCER

Background/Aims: Long term results of hepatic resection for metastases from colorectal cancer depend upon several factors which are related to both features of primary cancer and of metastases. The aim of this study was to evaluate prognostic factors that best correlate with long -term results. Materials and Methods: Fifty-eight hepatic resections w ere performed for colorectal cancer metastases. Long-term results were evaluated in. relation to age of patients, features of primary tumor, features of metastases, section margin, number of intra-operative blo od transfusions and execution of adjuvant chemotherapy. Results: Overa ll 5-year survival rate was 17%. 5-year survival rate in patients with stage B primary tumor was 63%, in patients with late metachronous met astases it was 28%, in patients with section margin > 1 cm it was 33% and in patients who did not receive intra-operative transfusions it wa s 45%. Patients with a solitary metastasis or with metastases sized le ss than. 4 cm and those who received adjuvant chemotherapy also showed a better survival than the others. Conclusions: Better results were o bserved in patients without nodal involvement of the primary tumor. Pa tients with a smalt solitary metachronous metastasis that appeared mor e than one year after the colorectal resection and resected with a sec tion. margin of more than 1 cm, also showed good results.