The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria

Authors
Zeidler, J Schwender, J Mueller, C Lichtenthaler, HK
Citation
J. Zeidler et al., The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria, BIOCH SOC T, 28, 2000, pp. 796-798
Citations number
15
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHEMICAL SOCIETY TRANSACTIONS
ISSN journal
03005127 → ACNP
Volume
28
Year of publication
2000
Part
6
Pages
796 - 798
Database
ISI
SICI code
0300-5127(200012)28:<796:TNIBOP>2.0.ZU;2-2
Abstract
Two plant test systems are presented in the search for flew inhibitors of t he non-mevalonate isoprenoid pathway. A derivative of clomazone appears to be an inhibitor of the deoxyxylulose 5-phosphate/methylerythritol 4-phospha te (DOXP/NIEP) pathway of isoprenoid formation.