F. Patriarca et al., Long-lasting complete remission of hepatitis C virus (HCV) infection and HCV-associated immunocytoma with alpha-interferon treatment, BR J HAEM, 112(2), 2001, pp. 370-372
Several epidemiological data suggest the involvement of hepatitis C virus (
HCV) in the pathogenesis of some histotypes of B-cell non-Hodgkin's lymphom
as, in particular immunocytoma. We report a patient with HCV-associated imm
unocytoma, first treated with six courses of fludarabine. A partial respons
e was achieved and subsequent therapy with alpha-interferon resulted in the
clearance of the virus and a long-lasting complete clinical and histologic
al remission of the lymphoproliferative disease.