Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites - Report from the UK700 trial

Citation
K. Mckenzie et al., Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites - Report from the UK700 trial, BR J PSYCHI, 178, 2001, pp. 160-165
Citations number
26
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry","Neurosciences & Behavoir
Journal title
BRITISH JOURNAL OF PSYCHIATRY
ISSN journal
00071250 → ACNP
Volume
178
Year of publication
2001
Pages
160 - 165
Database
ISI
SICI code
0007-1250(200102)178:<160:COTOAT>2.0.ZU;2-9
Abstract
Background The comparative outcome of psychosis in British Whites and UK Af rican-Caribbeans is unclear. Some report that African - Caribbeans have wor se outcome, whereas others claim better symptomatic outcome and a more beni gn course. Aims To a compare the course, outcome and treatment of psychosis in African Caribbeans and British Whites in a large multi-centre sample. Method A secondary analysis of 708 patients with research diagnostic criter ia defined psychosis from a 2-year, randomised controlled trial of case man agement. Outcome measures (hospitalisation, illness course, self-harm. soci al disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. Results African-Caribbeans were less likely to have a continuous illness an d to receive treatment with antidepressants or psychotherapy. Conclusions The outcome of psychosis is complex but differs between UK Afri can-Caribbeans and British Whites. This may reflect risk factors that incre ase the rate of psychosis in UK African Caribbeans. Treatment differences r equire further investigation.