Cancer Genomics or the molecular portraits of tumors

Authors
Citation
F. Sigaux, Cancer Genomics or the molecular portraits of tumors, B ACA N MED, 184(7), 2000, pp. 1441-1449
Citations number
12
Categorie Soggetti
General & Internal Medicine
Journal title
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
ISSN journal
00014079 → ACNP
Volume
184
Issue
7
Year of publication
2000
Pages
1441 - 1449
Database
ISI
SICI code
0001-4079(2000)184:7<1441:CGOTMP>2.0.ZU;2-F
Abstract
The rapid development of cancer genomics is due to important progresses in oncogenesis, human genome sequencing and emergence of new technologies in g enome and transcriptome analysis. In this context, the aim of the French pr ogram 'Cartes d'Identites des Tumeurs Molecular Portraits of Tumors' is to build a public data base containing a pan genome assessment of genome and t ranscriptome alterations in the major types of tumors as well as in relevan t normal cells and experimental models. Data mining is done in the context of genome annotations and clinical and biological informations attached to the enrolled samples. The goal of the program is to define new tests useful for diagnostic procedures in clinical laboratories and new targets for bio logical treatments of tumors.