First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

Authors
Jaouen, G Top, S Vessieres, A Pigeon, P Leclercq, G Laios, I
Citation
G. Jaouen et al., First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects, CHEM COMMUN, (4), 2001, pp. 383-384
Citations number
19
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
4
Year of publication
2001
Pages
383 - 384
Database
ISI
SICI code
1359-7345(2001):4<383:FAITCR>2.0.ZU;2-X
Abstract
A route to the organometallic complex 8 is described, along with a study of its antiproliferative effects on breast cancer cell lines; in the examples studied, 8 behaves in a very similar manner to tamoxifen, suggesting new p ossibilities for applications in organometallic chemistry.