Synthesis and biological activity of 3-methyl-1H- pyrazole-4-carboxylic ester derivatives

Authors
Zhao, WG Li, ZM Yuan, PW Wang, WY
Citation
Wg. Zhao et al., Synthesis and biological activity of 3-methyl-1H- pyrazole-4-carboxylic ester derivatives, CHIN J CHEM, 19(2), 2001, pp. 184-188
Citations number
8
Categorie Soggetti
Chemistry
Journal title
CHINESE JOURNAL OF CHEMISTRY
ISSN journal
1001604X → ACNP
Volume
19
Issue
2
Year of publication
2001
Pages
184 - 188
Database
ISI
SICI code
1001-604X(200102)19:2<184:SABAO3>2.0.ZU;2-Y
Abstract
In search of novel pyrazole derivatives with bioactivity, a series of 3-met hyl-1H-pyrazole-4-caboxylic ester derivatives were synthesized via alpha -o xoketene dithioacetals as starting material, The structures of all compound s prepared were confirmed by H-1 NMR, IR, MS and elemental analyses. Prelim inary bioassays indicated that some compounds showed fungicidal activity ag ainst wheat rust, phoma asparagi and antiviral activity against TMV.