The authors report abnormal Tc-99m sestamibi (MIBI) and TI-201 uptake in a
62-year-old patient with histologically and biochemically proved myeloma. T
I-201 imaging was undertaken for tumor evaluation, and 3 days later a Tc-99
m MIBI study showed diffuse and focal marrow uptake with focal skull lesion
s, whereas TI-201 did not show skull lesions. After treatment, follow-up Tc
-99m MIBI whale-body imaging was performed and the marrow uptake was decrea
sed.