Facial soft-tissue augmentation with allogeneic human tissue collagen matrix (dermalogen and dermaplant)

Soft-tissue augmentation has been established as a viable means of facial r ejuvenation where age-related or postsurgical changes manifest as contour o r structural defects, and is available for those who desire volume enhancem ent for various areas. A growing number of agents and techniques are curren tly available that when used appropriately, can improve or correct facial r hytides, regional volume depletion, and iatrogenic structural soft-tissue m alposition. Failures of some agents are caused by either reduced biocompati bility, inadequate technique of administration, or failure to match the act ual underlying pathology with the most appropriate solution. Soft-tissue au gmentation with allogenic human tissue collagen matrix by intradermal injec tion and surgically implantable forms, is physiologic, seems to be ultimate ly safe and effective, and heralds many qualities consistent with an ideal agent. Several allogenic (cadaver-derived), heterologous, and alloplastic a gents are discussed with regard to rationale, patient selection, optimum te chnique of administration, and persistence.