Nickel allergy is the most frequent contact allergy and is also one of the
major background factors for hand eczema. The clinical significance of nick
el release from coins was discussed when the composition of euro coins was
decided. Current European coinage is dominated by cupro-nickel coins (Cu 75
; Ni 25); other nickel-containing and non-nickel alloys are also used. Nick
el release from used coinage from the UK, Sweden and France was determined.
It was shown that nickel ions are readily available on the surface of used
coins. After 2 min in artificial sweat, approximately 2 mug of nickel per
coin was extracted from cupro-nickel coins. Less nickel was extracted from
non-nickel coins. Nickel on the surface was mainly present as chloride. Aft
er 1 week in artificial sweat approximately 30 mug/cm(2) was released from
cupro-nickel coins: less nickel was released from coins made of other nicke
l alloys. Theoretically, several mug of nickel salts may be transferred dai
ly onto hands by intense handling of high-nickel-releasing coins.