Microdeletion 4p16.3 in three unrelated patients with Wolf-Hirschhorn syndrome

Authors
Dufke, A Seidel, J Schoning, M Dobler-Neumann, M Kelbova, C Liehr, T Beensen, V Backsch, C Klein-Vogler, U Enders, H
Citation
A. Dufke et al., Microdeletion 4p16.3 in three unrelated patients with Wolf-Hirschhorn syndrome, CYTOG C GEN, 91(1-4), 2000, pp. 81-84
Citations number
19
Categorie Soggetti
Molecular Biology & Genetics
Journal title
CYTOGENETICS AND CELL GENETICS
ISSN journal
03010171 → ACNP
Volume
91
Issue
1-4
Year of publication
2000
Pages
81 - 84
Database
ISI
SICI code
0301-0171(2000)91:1-4<81:M4ITUP>2.0.ZU;2-4
Abstract
Wolf-Hirschhorn syndrome (WHS) is a multiple malformation syndrome caused b y partial monosomy of 4p16.3. Pitt-Rogers-Danks syndrome, first thought to be a distinct entity, is a similar condition associated with a microdeletio n overlapping the WHS critical region. In this paper we evaluate three WHS patients showing a microdeletion of 4p and remarkable development with resp ect to the clinical spectrum of WHS. Copyright (C) 2001 S. Karger AG, Basel .