In this research we examined stress-related correlates of hand preference i
n monkeys. Specifically we tested the hypothesis that stress reactivity and
plasma levels of the stress hormone cortisol are developmentally related t
o handedness in rhesus macaques (Macaca mulatta). We found a significant po
sitive correlation between cortisol levels sampled in juveniles and the fre
quency of right- versus left-hand use sampled in these same animals during
adulthood. Right-hand preference tvas negatively correlated with stress rea
ctivity. These data are consistent with the vier-v that stress functioning
and reactivity are associated with the development of hemispheric specializ
ation in primates (C) 2001 John Wiley & Sons, Inc.