The miaA mutator phenotype of Escherichia coli K-12 requires recombinationfunctions

Authors
Zhao, JY Leung, HCE Winkler, ME
Citation
Jy. Zhao et al., The miaA mutator phenotype of Escherichia coli K-12 requires recombinationfunctions, J BACT, 183(5), 2001, pp. 1796-1800
Citations number
38
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
183
Issue
5
Year of publication
2001
Pages
1796 - 1800
Database
ISI
SICI code
0021-9193(200103)183:5<1796:TMMPOE>2.0.ZU;2-I
Abstract
miaA mutants, which contain A-37 instead of the ms(2)i(6)A-37 hypermodifica tion in their tRNA, show a moderate mutator phenotype leading to increased GC->TA transversion. We show that the miaA. mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those r equired for translation stress-induced mutagenesis.