Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma

Authors
Kanamori, M Antonescu, CR Scott, M Bridge, RS Neff, JR Spanier, SS Scarborough, MT Vergara, G Rosenthal, HG Bridge, JA
Citation
M. Kanamori et al., Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in adamantinoma, J MOL DIAGN, 3(1), 2001, pp. 16-21
Citations number
13
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
JOURNAL OF MOLECULAR DIAGNOSTICS
ISSN journal
15251578 → ACNP
Volume
3
Issue
1
Year of publication
2001
Pages
16 - 21
Database
ISI
SICI code
1525-1578(200102)3:1<16:ECOC78>2.0.ZU;2-3
Abstract
Adamantinoma of long bones is a rare neoplasm predominantly involving the t ibia Cytogenetic studies of adamantinoma are few. Cytogenetic or molecular cytogenetic analysis of four adamantinomas, and a review of eleven cases in the literature reveals extra copies of chromosomes 7, 8, 12, 19, and 21 as recurrent in this neoplasm. Adamantinoma may be confused with a variety of primary and metastatic epithelial and mesenchymal neoplasms. Observation o f these aneuploidies may be useful in establishing the diagnosis of adamant inoma.