SPECT imaging brain perfusion using Tc-99m-HMPAO was performed on a 38
-yr-old woman with Lyme neuroborreliosis confirmed by autopsy. The pat
ient had been suspected of spinocerebellar degeneration. Cerebral bloo
d flow was diffusely decreased throughout cerebral cortices but cerebe
llar blood flow was not impaired, which indicated that the diagnosis w
as unlikely spinocerebellar degeneration. These findings suggested tha
t brain perfusion SPECT provides useful information in diagnosing the
patients with Lyme neuroborreliosis, especially when spinocerebellar d
egeneration is included in the differential diagnosis.