In this paper we describe the role that mathematics plays in measurement sc
ience at NIST. We first survey the history behind NIST's current work in th
is area, starting with the NBS Math Tables project of the 1930s. We then pr
ovide examples of more recent efforts in the application of mathematics to
measurement science, including the solution of ill-posed inverse problems,
characterization of the accuracy of software for micromagnetic modeling, an
d in the development and dissemination of mathematical reference data. Fina
lly, we comment on emerging issues in measurement science to which mathemat
icians will devote their energies in coming years.