A polymer-supported thionating reagent

Authors
Ley, SV Leach, AG Storer, RI
Citation
Sv. Ley et al., A polymer-supported thionating reagent, J CHEM S P1, (4), 2001, pp. 358-361
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
4
Year of publication
2001
Pages
358 - 361
Database
ISI
SICI code
1472-7781(2001):4<358:APTR>2.0.ZU;2-F
Abstract
A new polymer-supported reagent for the conversion of carbonyls to thiocarb onyls has been developed and its use demonstrated on a range of amides. Sec ondary or tertiary amides are converted cleanly and efficiently through to the corresponding thioamides and primary amides are converted to the corres ponding nitriles. The reactions can be facilitated by conventional heating. However, if microwave heating is used, in the presence of an ionic liquid, enhanced reaction rates are achieved.