Chronic heart failure (CHF) is principally a cardiogeriatric syndrome, and
it has become a major public health problem in the 21st century due largely
to the aging population. Age-related changes throughout the cardiovascular
system in combination with the high prevalence of cardiovascular diseases
at older age predispose older adults to the development of CHF, Features th
at distinguish CHF at advanced age from CHF occurring during middle age inc
lude an increasing proportion of women, a shift from coronary heart disease
to hypertension as the most common etiology, and the high percentage of ca
ses that occur in the setting of preserved left ventricular systolic functi
on. Although the pharmacotherapy of CHF is similar in older and younger pat
ients, the presence of multiple comorbidities in older patients mandates a
multidisciplinary approach to care. Manifest CHF is associated with a poor
prognosis, especially in elderly persons, and there is an urgent need to de
velop more effective strategies for the prevention and treatment of this in
creasingly common disorder to reduce the individual and societal burden of
this devastating illness in the decades ahead.