Primary intradural classic chondrosarcoma: Case report and literature review

OBJECTIVE AND IMPORTANCE: The exact origin of rare intradural chondrosarcom as remains obscure. We present a case report of an intradural classic chond rosarcoma (a very rave subtype of chondrosarcoma in this location), with a review of the literature, in an attempt to clarify the histogenesis of thes e tumors. CLINICAL PRESENTATION: A 48-year-old man presented with a 12-month history of progressive right hemiparesis. Computed tomography and magnetic resonanc e imaging demonstrated a left parietal space-occupying lesion. INTERVENTION: The patient underwent an image-guided, left parietal parasagi ttal craniotomy. An extrinsic tumor, which seemed to arise from the dura, w as macroscopically removed. There was no bone involvement. The histological examination revealed a Grade Il classic chondrosarcoma with tumor infiltra tion into the dura. Adjuvant radiotherapy was administered. CONCLUSION: Intradural chondrosarcomas are rare tumors, the majority of whi ch are mesenchymal. Classic chondrosarcomas in this location are much rarer . Their histogenesis is uncertain. In this case, the origin seems to be fro m the dura. Because of the malignant potential of these tumors, radical ext irpation whenever possible, followed by radiotherapy, is indicated.