Vilsmeier formylation of praziquantel: synthesis and application for polarographic assay

Citation
Ej. Kim et al., Vilsmeier formylation of praziquantel: synthesis and application for polarographic assay, PHARMAZIE, 56(2), 2001, pp. 146-149
Citations number
31
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
56
Issue
2
Year of publication
2001
Pages
146 - 149
Database
ISI
SICI code
0031-7144(200102)56:2<146:VFOPSA>2.0.ZU;2-V
Abstract
A simple and sensitive method for the polarographic determination of praziq uantel (1) after derivatization using Vilsmeier formylation is, described. The polarographically active compound obtained by this procedure has been s eparated, identified and prepared using N,N-dimethylformamide and phosphoru s oxychloride.