Spectrophotometric and HPLC determination of fleroxacin in tablets

Authors
Milovanovic, L Kapetanovic, V Popovic, G Dugumovic, Z Miljevic, D Aleksic, M
Citation
L. Milovanovic et al., Spectrophotometric and HPLC determination of fleroxacin in tablets, PHARMAZIE, 56(2), 2001, pp. 150-151
Citations number
15
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
56
Issue
2
Year of publication
2001
Pages
150 - 151
Database
ISI
SICI code
0031-7144(200102)56:2<150:SAHDOF>2.0.ZU;2-A
Abstract
The paper describes and compares spectrophotometric and HPLC determination of fleroxacin in commercial tablets. The optimum conditions for spectrophot ometric assay were found to be at pH < 3.5 (0.1 M HCl) at a wave length of 286 nm. HPLC analysis was carried out on a Beckman ODS 5 <mu>m column in a pH 3 phosphoric acid solution (detector wave length 254 nm).