From ancient remedies to modern therapeutics: Pine bark uses in skin disorders revisited

Authors
Rihn, B Saliou, C Bottin, MC Keith, G Packer, L
Citation
B. Rihn et al., From ancient remedies to modern therapeutics: Pine bark uses in skin disorders revisited, PHYTOTHER R, 15(1), 2001, pp. 76-78
Citations number
6
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
15
Issue
1
Year of publication
2001
Pages
76 - 78
Database
ISI
SICI code
0951-418X(200102)15:1<76:FARTMT>2.0.ZU;2-8
Abstract
The effect of French maritime pine bark extract (PBE) on the gene expressio n profile of HaCaT human keratinocytes was studied using high density filte r arrays. The expression profile of both control and PBE-treated cells was determined, Interestingly, PBE was shown to downregulate both calgranulin A and B genes which are known to be upregulated in psoriasis and various der matoses, Thus, PBE could be considered in human dermatoses, Copyright (C) 2 001 John Wiley & Sons, Ltd.