A one-pot method for the efficient preparation of aromatic nitriles from aldehydes using ammonia, magnesium sulfate, and manganese dioxide

Authors
Lai, GF Bhamare, NK Anderson, WK
Citation
Gf. Lai et al., A one-pot method for the efficient preparation of aromatic nitriles from aldehydes using ammonia, magnesium sulfate, and manganese dioxide, SYNLETT, (2), 2001, pp. 230-231
Citations number
28
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
2
Year of publication
2001
Pages
230 - 231
Database
ISI
SICI code
0936-5214(200102):2<230:AOMFTE>2.0.ZU;2-8
Abstract
A one-pot and efficient preparation of aromatic nitriles from the correspon ding aldehydes was accomplished by treatment with 2 M ammonia solution in 2 -propanol, magnesium sulfate, and manganese dioxide in THF at room temperat ure. This method was found to be compatible with a variety of functionaliti es such as hydroxyl, ester, and amide.