2,4,6-Tri-tert-butylpyrimidine (TTBP): A cost effective, readily availablealternative to the hindered base 2,6-Di-tert-butylpyridine and its 4-substituted derivatives in glycosylation and other reactions

Authors
Crich, D Smith, M Yao, QJ Picione, J
Citation
D. Crich et al., 2,4,6-Tri-tert-butylpyrimidine (TTBP): A cost effective, readily availablealternative to the hindered base 2,6-Di-tert-butylpyridine and its 4-substituted derivatives in glycosylation and other reactions, SYNTHESIS-S, (2), 2001, pp. 323-326
Citations number
35
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
2
Year of publication
2001
Pages
323 - 326
Database
ISI
SICI code
0039-7881(200102):2<323:2(ACER>2.0.ZU;2-1
Abstract
It is reported that 2,4,6-tri-tert-butylpyrimidine (TTBP), a highly sterica lly hindered base available through an efficient, cost-effective one pot se quence, is a replacement for 2,6-di-tert-butylpyridine and its 4-substitute d analogs in glycosylation reactions and in the formation of vinyl triflate s.